| Post: | First Lady |
| Body: | Tajikistan |
| Insignia: | File:Flag of the President of Tajikistan.svg |
| Insigniasize: | 75px |
| Insigniacaption: | Presidential Standard |
| Incumbent: | Azizmo Asadullayeva |
| Residence: | Palace of Nations, Dushanbe |
| Incumbentsince: | 7 September 1992 |
| Preceded By: | First Lady of the Tajik SSR |
| Termlength: | 7 years |
| Formation: | 2 December 1991 |
| Inaugural: | Gavkhar Makhkamova |
| Native Name: | Якум зане дар Тоҷикистон |
First Lady of Tajikistan is the title attributed to the wife of the President of Tajikistan. The current first lady of Tajikistan is Azizmo Asadullayeva, wife of President Emomali Rahmon.
| No. | Image | Name | Term Begins | Term Ends | President of Tajikistan | President image | |
|---|---|---|---|---|---|---|---|
| 1 | Gavkhar Makhkamova[1] [2] [3] | 30 November 1990 | 31 August 1991 | Qahhor Mahkamov | |||
| 2 | Mariam Nabieva[4] | 2 December 1991 | 7 September 1992 | Rahmon Nabiyev | |||
| 3 | Azizmo Asadullayeva[5] | 7 September 1992 | Present | Emomali Rahmon |