| Post: | First Lady |
| Body: | Cape Verde |
| Insignia: | Flag of Cape Verde.svg |
| Insigniasize: | 100px |
| Incumbent: | Débora Katisa Carvalho |
| Incumbentsince: | 9 November 2021 |
| Residence: | Presidential Palace of Cape Verde |
| Termlength: | 5 years |
| Formation: | July 8, 1975 |
| Inaugural: | Carlina Pereira |
First Lady of Cape Verde is the title attributed to the wife of the president of Cape Verde. The position is currently vacant.
| Name | Portrait | Term Began | Term Ended | President of Cape Verde | Notes | ||
|---|---|---|---|---|---|---|---|
| 1 | Carlina Pereira | 22 March 1975 | 22 March 1991 | Aristides Pereira | Independence activist and inaugural First Lady of Cape Verde.[1] | ||
| 2 | Tuna Mascarenhas | 22 March 1991 | 22 March 2001 | António Mascarenhas Monteiro | Mascarenhas continued to work at the clinical analysis laboratory at Agostinho Neto Hospital during her two terms as first lady.[2] | ||
| 3 | Adélcia Barreto Pires | 22 March 2001 | 9 September 2011 | Pedro Pires | |||
| 4 | Ligia Fonseca | 9 September 2011 | 9 November 2021 | Jorge Carlos Fonseca | |||
| 5 | Débora Katisa Carvalho | 9 November 2021 | José Maria Neves |