| Post: | First Lady |
| Body: | Gabon |
| Insignia: | Flag of Gabon.svg |
| Insigniasize: | 100px |
| Incumbent: | Zita Nyangue Oligui Nguema |
| Residence: | Presidential Palace, Liberville |
| Incumbentsince: | August 30, 2023 |
| Termlength: | No term limit/No term for First Lady. |
| Formation: | February 12, 1961 |
| Inaugural: | Pauline M'ba |
First Lady or First Gentleman of Gabon[1] is the title held by the spouse of the president of Gabon. The current first lady is Zita Nyangue Oligui Nguema, wife of Brice Oligui, the Transitional President of Gabon.
| Name | Term begins | Term ends | President of Gabon |
|---|---|---|---|
| Pauline M'ba | 12 February 1961 | 27 November 1967 | Léon M'ba |
| Patience Dabany | 27 November 1967 | 1987 (Divorced) | Omar Bongo |
| Position vacant | 1987 | August 4, 1989 | Omar Bongo |
| Edith Lucie Bongo | August 4, 1989 (Marriage to Bongo) | March 14, 2009 (Died in Office) | Omar Bongo |
| Position vacant | March 14, 2009 | 8 June 2009 | Vacant |
| 10 June 2009 | 16 October 2009 | Rose Francine Rogombé (Acting) | |
| Sylvia Bongo Ondimba | 16 October 2009 | 30 August 2023 | Ali Bongo Ondimba |
| Zita Nyangue Oligui Nguema | 30 August 2023 | Present | Brice Clotaire Oligui Nguema |