Filicin Explained
Filicin is a chemical compound that has been isolated from ferns of the genus Dryopteris. It has been isolated from the male fern (Dryopteris filix-mas).[1] Filicin has been studied for its anthelmintic activity.[2]
Related compounds
A variety of chemically related compounds, sometimes referred to collectively as, have also been isolated from ferns. Chemical analysis of in fern extracts can assist in determining taxonomy.[3] Examples of include:
| Name(s) | Chemical structure | Molecular formula | Molecular weight (g/mol) | CAS number | PubChem | Notes and
references |
|---|
| Filixic acid ABA | | C32H36O12 | 612.63 | 38226-84-5 | | First isolated from Dryopteris dickinsii[4] |
| Filixic acid ABP | | C33H38O12 | 626.66 | 57765-54-5 | | |
| Filixic acid ABB | | C34H40O12 | 640.68 | 37318-24-4 | | Found in Dryopteris sieboldii[5] |
| Filixic acid PBP | | C34H40O12 | 640.68 | 51005-85-7 | | Found in Dryopteris sieboldii and Dryopteris filix-mas |
| Filixic acid PBB | | C35H42O12 | 654.71 | 49582-09-4 | | [6] |
| Flavaspidic acid BB; Toxifren; Polystichocitrin; Glavaspidic acid | | C24H30O8 | 446.49 | 114-42-1 | | Isolated from Dryopteris abbreviata[7] | |
Notes and References
- Web site: Filicin . TOXNET . U.S. National Library of Medicine.
- 13953368. 1963. Heikinheimo. R. Effect of filicin administered as an anthelmintic on the coagulation factors of the blood. Annales Medicinae Internae Fenniae. 52. 93–6.
- Chemotaxonomy in Dryopteris and related fern genera . Euw, J. v. . Lounasmaa, M. . Reichstein, T. . Widén, C.J. . Studia Geobotanica . 1 . 1980 . 275–311.
- Pharmaceutical studies on Japanese ferns containing phloroglucinol derivatives. 9 Constituents of Dryopteris dickinsii . Hisada, Sueo . Shiraishi, Koichi . Inagaki, Isao . Yakugaku Zasshi . 1972 . 92 . 9 . 1124–1128 . 10.1248/yakushi1947.92.9_1124. free .
- Phloroglucinol derivatives of Dryopteris sieboldii . Hisada, Sueo . Inoue, O. . Inagak, Isao . Phytochemistry . 1973 . 12 . 8 . 2055 . 10.1016/s0031-9422(00)91535-8.
- 1197418. 1975. Widén. C. J. Phloroglucinol derivatives of eleven Dryopteris species from Japan. Planta Medica. 28. 2. 144–64. Lounasmaa. M. Sarvela. J.
- 10.1016/0031-9422(82)80168-4. A phloroglucinol derivative of Dryopteris abbreviata. Phytochemistry. 21. 6. 1453. 1982. Coşkun. Maksut. Sakushima. Akiyo. Nishibe. Sansei. Hisada. Sueo. Tanker. Nevin.
