Fenticlor Explained

Fenticlor (also spelled fentichlor) is an antibacterial and antifungal agent for topical use. It is an antimicrobial agent. It is also used in veterinary medicine.__TOC__

Synthesis

It is prepared by the AlCl₃-catalyzed reaction of 4-chlorophenol with sulfur dichloride. It can also be prepared by chlorination of bis[2-hydroxyphenyl]sulfide.^{[1] [2]}

Safety

The (rats, oral) of fenticlor is 3250 mg/kg. It may cause photosensitivity.^[3]

Notes and References

1. DE . 568944 .
2. 10.1021/ja01360a035. Preparation and Bacteriological Study of Some Symmetrical Organic Sulfides. Journal of the American Chemical Society. 53. 9. 3466–3469. 1931. Dunning F, Dunning B, Drake WE .
3. Burry JN . Letter: Fenticlor, actinic reticuloid, and antihistamines . British Medical Journal . 2 . 5918 . 556–7 . June 1974 . 4152080 . 1610938 . 10.1136/bmj.2.5918.556-c .