Fc receptor, IgA, IgM, high affinity | |
Hgncid: | 24692 |
Symbol: | FCAMR, CD351 |
Entrezgene: | 83953 |
Omim: | 605484 |
Refseq: | NM_032029 |
Uniprot: | Q96SA2 |
Chromosome: | 1 |
Arm: | q |
Band: | 32.1 |
Fcα/μR, also known as is CD351 (Cluster of Differentiation 351), is an Fc receptor that binds IgM with high affinity and IgA with a 10-fold lower affinity.[1] In mice the receptor is expressed on macrophages, follicular dendritic cells, marginal zone B cells, follicular B cells, and kidney tubular epithelial cells. In humans expression has been described on intestinal lamina propria cells, Paneth cells, follicular dendritic cells in tonsils, activated macrophages and some types of pre-germinal centre IgD+/CD38+ B cells.