| Fazenda São Mateus Biological Reserve | |
| Iucn Category: | Ia |
| Relief: | yes |
| Designation: | Biological reserve |
| Created: | 23 September 1974 |
| Administrator: | Instituto Estadual de Florestas – Minas Gerais |
Fazenda São Mateus Biological Reserve was a biological reserve in Minas Gerais, Brazil.
The biological reserve was created by Law 16.580 of 23 September 1974 with an area of in the municipality of Ponte Nova, Minas Gerais.An audit in 2012 stated that a number of biological reserves created in 1974 on state-owned land were being re-assessed, since they no longer qualified as conservation units.These were Fazenda São Mateus, Carmo da Mata, Colônia 31 de Março and others.As of 2016 the reserve did not appear on the list of biological reserves in the state.