| Honorific-Prefix: | Most Reverend |
| Fabrizio Degli Afflitti | |
| Bishop of Boiano | |
| Church: | Catholic Church |
| Diocese: | Diocese of Boiano |
| Term: | 1608–1613 |
| Predecessor: | Carlo Carafa (bishop) |
| Successor: | Pietro Paolo Eustachi |
| Consecration: | 23 November 1608 |
| Consecrated By: | Marcello Lante della Rovere |
| Birth Date: | 1572 |
| Birth Place: | Naples, Italy |
| Death Date: | 1613 (age 41) |
| Death Place: | Boiano, Italy |
Fabrizio Degli Afflitti (1572–1613) was a Catholic prelate who served as Bishop of Boiano (1608–1613).[1]
Fabrizio Degli Afflitti was born in Naples, Italy.[2] On 10 November 1608, he was appointed by Pope Paul V as Bishop of Boiano. On 23 November 1608, he was consecrated bishop by Marcello Lante della Rovere, Bishop of Todi with Giovanni Battista del Tufo, Bishop of Acerra, and Paolo De Curtis, Bishop of Isernia, serving as principal co-consecrators. He served as Bishop of Boiano until his death in 1613.