FUT5 explained

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT5 gene.^{[1] [2]}

Further reading

• Chiu PC, Chung MK, Koistinen R, Koistinen H, Seppala M, Ho PC, Ng EH, Lee KF, Yeung WS . Glycodelin-A interacts with fucosyltransferase on human sperm plasma membrane to inhibit spermatozoa-zona pellucida binding . Journal of Cell Science . 120 . Pt 1 . 33–44 . January 2007 . 17148576 . 10.1242/jcs.03258 . free . 10722/45488 . free .
• Inaba Y, Ohyama C, Kato T, Satoh M, Saito H, Hagisawa S, Takahashi T, Endoh M, Fukuda MN, Arai Y, Fukuda M . Gene transfer of alpha1,3-fucosyltransferase increases tumor growth of the PC-3 human prostate cancer cell line through enhanced adhesion to prostatic stromal cells . International Journal of Cancer . 107 . 6 . 949–57 . December 2003 . 14601054 . 10.1002/ijc.11513 . 7078688 . free .
• Roos C, Kolmer M, Mattila P, Renkonen R . Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism . The Journal of Biological Chemistry . 277 . 5 . 3168–75 . February 2002 . 11698403 . 10.1074/jbc.M107927200 . free .
• Nishihara S, Iwasaki H, Kaneko M, Tawada A, Ito M, Narimatsu H . Alpha1,3-fucosyltransferase 9 (FUT9; Fuc-TIX) preferentially fucosylates the distal GlcNAc residue of polylactosamine chain while the other four alpha1,3FUT members preferentially fucosylate the inner GlcNAc residue . FEBS Letters . 462 . 3 . 289–94 . December 1999 . 10622713 . 10.1016/S0014-5793(99)01549-5 . 37842289 . free .
• McCurley RS, Recinos A, Olsen AS, Gingrich JC, Szczepaniak D, Cameron HS, Krauss R, Weston BW . Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21 . Genomics . 26 . 1 . 142–6 . March 1995 . 7782074 . 10.1016/0888-7543(95)80094-3 .
• Cameron HS, Szczepaniak D, Weston BW . Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms . The Journal of Biological Chemistry . 270 . 34 . 20112–22 . August 1995 . 7650030 . 10.1074/jbc.270.34.20112 . free .
• Weston BW, Smith PL, Kelly RJ, Lowe JB . Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes . The Journal of Biological Chemistry . 267 . 34 . 24575–84 . December 1992 . 10.1016/S0021-9258(18)35803-4 . 1339443 . free .

Notes and References

1. Weston BW, Nair RP, Larsen RD, Lowe JB . Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities . The Journal of Biological Chemistry . 267 . 6 . 4152–60 . February 1992 . 10.1016/S0021-9258(19)50641-X . 1740457 . free .
2. Web site: Entrez Gene: FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase).