FOXI3 explained

Forkead box I3 (FOXI3) is a protein that in humans is encoded by the FOXI3 gene. FOXI3 is a forkhead box transcription factor that is expressed in the development of hair and teeth. One of its mutations is a dominant allele responsible for the heterozygous Hh hairless trait in dogs. It was identified in 2008.^[1]

See also

• Chinese Crested Dog
• Mexican Hairless Dog
• Peruvian Inca Orchid (Peruvian Hairless Dog)
• Dog coat genetics

Notes and References

1. Drögemüller C, Karlsson EK, Hytönen MK, Perloski M, Dolf G, Sainio K, Lohi H, Lindblad-Toh K, Leeb T . 6 . A mutation in hairless dogs implicates FOXI3 in ectodermal development . Science . 321 . 5895 . 1462 . September 2008 . 18787161 . 10.1126/science.1162525 . 2008Sci...321.1462D . 206514824 .