FLVCR1 explained
Feline leukemia virus subgroup C receptor-related protein 1 is a protein that in humans is encoded by the FLVCR1 gene (SLC49A1).[1] [2] [3] [4]
Further reading
- Lipovich L, Hughes AL, King MC, Abkowitz JL, Quigley JG . Genomic structure and evolutionary context of the human feline leukemia virus subgroup C receptor (hFLVCR) gene: evidence for block duplications and de novo gene formation within duplicons of the hFLVCR locus . Gene . 286 . 2 . 203–13 . 2002 . 11943475 . 10.1016/S0378-1119(02)00457-2 .
- Quigley JG, Yang Z, Worthington MT, Phillips JD, Sabo KM, Sabath DE, Berg CL, Sassa S, Wood BL, Abkowitz JL . Identification of a human heme exporter that is essential for erythropoiesis . Cell . 118 . 6 . 757–66 . 2004 . 15369674 . 10.1016/j.cell.2004.08.014 . 12749187 . free .
- Quigley JG, Gazda H, Yang Z, Ball S, Sieff CA, Abkowitz JL . Investigation of a putative role for FLVCR, a cytoplasmic heme exporter, in Diamond-Blackfan anemia . Blood Cells Mol. Dis. . 35 . 2 . 189–92 . 2006 . 15996880 . 10.1016/j.bcmd.2005.01.005 .
- Brown JK, Fung C, Tailor CS . Comprehensive mapping of receptor-functioning domains in feline leukemia virus subgroup C receptor FLVCR1 . J. Virol. . 80 . 4 . 1742–51 . 2006 . 16439531 . 1367145 . 10.1128/JVI.80.4.1742-1751.2006 .
Notes and References
- Tailor CS, Willett BJ, Kabat D . A putative cell surface receptor for anemia-inducing feline leukemia virus subgroup C is a member of a transporter superfamily . J. Virol. . 73 . 8 . 6500–5 . 1999 . 10.1128/JVI.73.8.6500-6505.1999 . 10400745 . 112732 .
- Quigley JG, Burns CC, Anderson MM, Lynch ED, Sabo KM, Overbaugh J, Abkowitz JL . Cloning of the cellular receptor for feline leukemia virus subgroup C (FeLV-C), a retrovirus that induces red cell aplasia . Blood . 95 . 3 . 1093–9 . 2000 . 10648427 . 10.1182/blood.V95.3.1093.003k01_1093_1099.
- Web site: Entrez Gene: FLVCR feline leukemia virus subgroup C cellular receptor.
- Crielaard. Bart J.. Lammers. Twan. Rivella. Stefano. 2017-02-03. Targeting iron metabolism in drug discovery and delivery. Nature Reviews Drug Discovery. en. advance online publication. 6. 400–423. 10.1038/nrd.2016.248. 28154410. 5455971. 1474-1784.