FKBP7 explained
FK506 binding protein 7 is a protein that in humans is encoded by the FKBP7 gene.[1] The gene is also known as FKBP23 and PPIase.[1] FKBP7 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. The orthologous protein in mouse is located in the endoplasmic reticulum and binds calcium.[1] [2]
Further reading
- Patterson . C. E. . Gao . J. . Rooney . A. P. . Davis . E. C. . Genomic Organization of Mouse and Human 65 kDa FK506-Binding Protein Genes and Evolution of the FKBP Multigene Family . 10.1006/geno.2002.6777 . Genomics . 79 . 6 . 881–889 . 2002 . 12036304 .
- Matsuda . M. . Koide . T. . Yorihuzi . T. . Hosokawa . N. . Nagata . K. . Molecular Cloning of a Novel Ubiquitin-like Protein, UBIN, That Binds to ER Targeting Signal Sequences . 10.1006/bbrc.2000.4149 . Biochemical and Biophysical Research Communications . 280 . 2 . 535–540 . 2001 . 11162551 .
Notes and References
- Web site: FK506 binding protein 7. 2011-12-06.
- Nakamura . T. . Yabe . D. . Kanazawa . N. . Tashiro . K. . Sasayama . S. . Honjo . T. . 10.1006/geno.1998.5571 . Molecular Cloning, Characterization, and Chromosomal Localization of FKBP23, a Novel FK506-Binding Protein with Ca2+-Binding Ability . Genomics . 54 . 1 . 89–98 . 1998 . 9806833 .