FIZ1 explained
FLT3 interacting zinc finger 1 is a protein that in humans is encoded by the FIZ1 gene.[1]
Function
This gene encodes zinc finger protein, which interacts with a receptor tyrosine kinase involved in the regulation of hematopoietic and lymphoid cells. This gene product also interacts with a transcription factor that regulates the expression of rod-specific genes in retina. [provided by RefSeq, Jul 2008].
Further reading
- Mitton KP, Swain PK, Khanna H, Dowd M, Apel IJ, Swaroop A . Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor . Hum. Mol. Genet. . 12 . 4 . 365–73 . February 2003 . 12566383 . 10.1093/hmg/ddg035. free .
- Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP . FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro . Exp. Eye Res. . 84 . 2 . 349–60 . February 2007 . 17141759 . 5066392 . 10.1016/j.exer.2006.10.009 .
Notes and References
- Web site: Entrez Gene: FLT3 interacting zinc finger 1. 2018-05-22.
