FDU-PB-22 explained

FDU-PB-22 is a derivative of JWH-018 that is presumed to be a potent agonist of the CB1 receptor, and has been sold online as a designer drug.[1] [2]

Pharmacology

FDU-PB-22 acts as a full agonist with a binding affinity of 1.19nM at CB1 and 2.43nM at CB2 cannabinoid receptors.[3]

Legal status

FDU-PB-22 is a controlled substance in Germany and is banned in Japan and Sweden.[4]

See also

Notes and References

  1. Web site: FDU-PB-22 . Southern Association of Forensic Scientists . 23 July 2015 . https://web.archive.org/web/20150527210102/http://forendex.southernforensic.org/index.php/detail/index/1279 . 27 May 2015 . dead .
  2. Uchiyama N, Shimokawa Y, Kikura-Hanajiri R, Demizu Y, Goda Y, Hakamatsuka T . N-OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal products . Forensic Toxicology . 33 . 2 . 244–259 . 1 July 2015 . 26257833 . 4525202 . 10.1007/s11419-015-0268-7 .
  3. Hess C, Schoeder CT, Pillaiyar T, Madea B, Müller CE . Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice . Forensic Toxicology . 34 . 2 . 329–343 . 1 July 2016 . 27429655 . 4929166 . 10.1007/s11419-016-0320-2 .
  4. Web site: Cannabinoider föreslås bli klassificerade som hälsofarlig vara . Folkhälsomyndigheten . 28 May 2014 . 23 July 2015.

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