FAUC50 explained

FAUC50 is a covalent agonist of the β2 adrenoceptor.[1] It has been used as a template to form covalent agonists for other receptors.[2]

Notes and References

  1. Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK . Structure and function of an irreversible agonist-β(2) adrenoceptor complex . Nature . 469 . 7329 . 236–40 . January 2011 . 21228876 . 3074335 . 10.1038/nature09665 . 2011Natur.469..236R .
  2. Weichert D, Kruse AC, Manglik A, Hiller C, Zhang C, Hübner H, Kobilka BK, Gmeiner P . Covalent agonists for studying G protein-coupled receptor activation . Proceedings of the National Academy of Sciences of the United States of America . 111 . 29 . 10744–8 . July 2014 . 25006259 . 4115510 . 10.1073/pnas.1410415111 . 2014PNAS..11110744W . free .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "FAUC50".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.