F-2 (drug) explained

F-2, or 6-(2-aminopropyl)-5-methoxy-2-methyl-2,3-dihydrobenzofuran, is a lesser-known psychedelic drug. F-2 was first synthesized by Alexander Shulgin. In his book PiHKAL, the minimum dosage is listed as 15 mg, and the duration unknown.^[1] F-2 produces few to no effects at this dose in humans. Animal studies showed it to substitute for the psychedelic drug DOM, but with less than one tenth the potency.^[2]

Legality

United Kingdom

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.^[3]

See also

• F-22 (psychedelic)
• Substituted benzofuran

Notes and References

1. vanc. F-2 Entry in PiHKAL
2. Nichols DE, Hoffman AJ, Oberlender RA, Riggs RM . Synthesis and evaluation of 2,3-dihydrobenzofuran analogues of the hallucinogen 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane: drug discrimination studies in rats . Journal of Medicinal Chemistry . 29 . 2 . 302–4 . February 1986 . 3950910 . 10.1021/jm00152a022 .
3. Web site: UK Misuse of Drugs act 2001 Amendment summary . 12 March 2014 . Isomer Design . 22 October 2017 . https://web.archive.org/web/20171022085110/http://isomerdesign.com/Cdsa/scheduleUK.php?schedule=1&ion=30&structure=C . dead .