| Eyre | |
| Name Etymology: | Edward John Eyre |
| Pushpin Map: | Australia South Australia |
| Pushpin Map Caption: | Location of the river mouth in South Australia |
| Subdivision Type1: | Country |
| Subdivision Name1: | Australia |
| Subdivision Type2: | State |
| Subdivision Name2: | South Australia |
| Subdivision Type3: | Region |
| Subdivision Name3: | Mid North |
| Source1 Location: | near Mount Horrocks |
| Mouth: | confluence with the Wakefield River |
| Custom Label: | Waterhole |
| Extra: | [1] |
The Eyre Creek is an ephemeral watercourse located in the Mid North region of the Australian state of South Australia.
The creek rises east of Mount Horrocks and drains south through and before reaching its confluence with the Wakefield River north of in the Clare Valley. The creek runs along Main North Road.
The creek was named in honour of Edward John Eyre, who explored the area in 1839 during one of his expeditions.