Symbol: | Exonuc_VII_L |
Exonuclease VII, large subunit | |
Pfam: | PF02601 |
Interpro: | IPR020579 |
Symbol: | Exonuc_VII_S |
Exonuclease VII small subunit | |
Pfam: | PF02609 |
Interpro: | IPR003761 |
The enzyme exodeoxyribonuclease VII (EC 3.1.11.6, Escherichia coli exonuclease VII, E. coli exonuclease VII, endodeoxyribonuclease VII, exodeoxyribonuclease VII) is a bacterial exonuclease enzyme.[1] [2] It is composed of two nonidentical subunits; one large subunit and 4 small ones.[3] that catalyses exonucleolytic cleavage in either 5′- to 3′- or 3′- to 5′-direction to yield nucleoside 5′-phosphates. The large subunit also contains an N-terminal OB-fold domain that binds to nucleic acids.