Eutylone Explained

Eutylone (also known as β-keto-1,3-benzodioxolyl-N-ethylbutanamine, bk-EBDB, and N-ethylbutylone) is a stimulant and empathogenic compound developed in the 1960s,[1] [2] which is classified as a designer drug.[3] It was first reported to the EMCDDA in 2014 and became widespread internationally in 2019-2020 following bans on the related compound ephylone.[4] [5] [6] [7] It is a synthetic cathinone.[7] In 2021, eutylone was the most common cathinone identified by the Drug Enforcement Administration in the United States.[8]

Legal status

Sweden's public health agency suggested classifying eutylone as a hazardous substance, on September 25, 2019.[9]

In the United States Eutylone is considered a schedule 1 controlled substance as a positional isomer of Pentylone.[10] [11]

See also

Notes and References

  1. GB. 108513. 1967-09-27. Aryl-α-aminoketone derivatives. Boehringer Ingelheim.
  2. Glatfelter GC, Walther D, Evans-Brown M, Baumann MH . Eutylone and Its Structural Isomers Interact with Monoamine Transporters and Induce Locomotor Stimulation . ACS Chemical Neuroscience . 12 . 7 . 1170–1177 . April 2021 . 33689284 . 10.1021/acschemneuro.0c00797 . 9423000 . 232192447 .
  3. Web site: Eutylone . 12 November 2023 . New Synthetic Drugs Database.
  4. Bade R, White JM, Nguyen L, Tscharke BJ, Mueller JF, O'Brien JW, Thomas KV, Gerber C . 6 . Determining changes in new psychoactive substance use in Australia by wastewater analysis . The Science of the Total Environment . 731 . 139209 . August 2020 . 32417485 . 10.1016/j.scitotenv.2020.139209 . 2020ScTEn.731m9209B . 218680033 .
  5. Krotulski AJ, Papsun DM, Chronister CW, Homan J, Crosby MM, Hoyer J, Goldberger BA, Logan BK . 6 . Eutylone Intoxications-An Emerging Synthetic Stimulant in Forensic Investigations . Journal of Analytical Toxicology . August 2020 . 45 . 1 . 8–20 . 33325503 . 10.1093/jat/bkaa113 . free .
  6. Chen HY, Chien WC, Huang MN, Fang CC, Weng TI . Analytically confirmed eutylone (bk-EBDB) exposure in emergency department patients . Clinical Toxicology . 846–848 . January 2021 . 59 . 9 . 33448882 . 10.1080/15563650.2020.1868491 . 231611658 .
  7. Nakamura M, Takaso M, Takeda A, Hitosugi M . A fatal case of intoxication from a single use of eutylone: Clinical symptoms and quantitative analysis results . Leg Med (Tokyo) . 58 . 102085 . September 2022 . 35537301 . 10.1016/j.legalmed.2022.102085 . 248602483 .
  8. Web site: Emerging Threat Report . 2021 .
  9. Web site: Tretton ämnen föreslås klassas som narkotika eller hälsofarlig vara . Folkhälsomyndigheten . sv . 25 September 2019 . 11 November 2019 . 31 October 2019 . https://web.archive.org/web/20191031144424/https://www.folkhalsomyndigheten.se/nyheter-och-press/nyhetsarkiv/2019/september/tretton-amnen-foreslas-klassas-som-narkotika-eller-halsofarlig-vara/ . dead .
  10. https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf Lists of: Scheduling Actions. Controlled Substances. Regulated Chemicals
  11. Web site: Federal Register :: Request Access .