| Country: | EUR |
| Map Custom: | yes |
| Type: | E |
| Route: | 64 |
| Length Km: | 246 |
| Direction A: | West |
| Terminus A: | Turin |
| Direction B: | East |
| Terminus B: | Brescia |
| Countries: |  Italy |
European route E 64 is a series of roads in Italy, part of the United Nations International E-road network.
It runs from Turin to Brescia, both in Italy.
Firstly it leaves Turin (in Piedmont), heading northeast into Lombardy and passing through Milan. It then continues north-east until it reaches its final destination of Brescia.