| Country: | EUR |
| Type: | E |
| Route: | 461 |
| Length Km: | 202 |
| Terminus A: | Svitavy (Czech Republic) |
| Junction: | Brno |
| Terminus B: | Vienna (Austria) |
| Countries: |  Czech Republic Austria |
E 461 is a European B class road in Czech Republic and Austria, connecting the cities Svitavy, Brno, and Vienna.