| Country: | ITA |
| Type: | E |
| Route: | 35 |
| Map: | Italia - mappa strada europea E35.svg |
| Direction A: | North |
| Terminus A: | at Switzerland border |
| Direction B: | South |
| Terminus B: | Rome |
European route E 35 (E 35) is a north–south European route, running from Amsterdam in the Netherlands to Rome in Italy. In Italy, the highway runs from the Swiss border near Como, to its southern terminus in Rome.