| Country: | EUR |
| Type: | E |
| Route: | 006 |
| Length Km: | 300 |
| Terminus A: | Ayni |
| Terminus B: | Kokand |
| Countries: |  Tajikistan Uzbekistan |
E 006 is a European B class road in Tajikistan and Uzbekistan, connecting the cities Ayni – Kokand. Since European routes are not signposted in Tajikistan and Uzbekistan, the E006 has never seen in a direction sign in any form.[1]