| Tourney Name: | European Cup |
| Year: | 1964–65 |
| Dates: | 13 September 1964 – 27 May 1965 |
| Num Teams: | 31 |
| Champion Other: |  Inter Milan |
| Count: | 2 |
| Second Other: | Benfica |
| Matches: | 63 |
| Goals: | 215 |
| Attendance: | 2213373 |
| Top Scorer: | Eusébio (Benfica) José Augusto Torres (Benfica) (9 goals each) |
| Prevseason: | 1963–64 |
| Nextseason: | 1965–66 |
The 1964–65 European Cup, the 10th season of the football club tournament, was won by Internazionale for the second time in row, in a final match against two-time former champions Benfica, making it three consecutive titles for Italy (Milan had won it in 1962–63).
Iceland entered its champion for the first time this season, while Cyprus did not enter this time around.
|}
1 Rangers won a play-off 3–1.
2 Anderlecht won a coin toss after their play-off match ended 0–0.
3 Dukla Prague won a coin toss after their play-off match ended 0–0.
Note: Starting the previous year tournament, only the title holder, Internazionale, joined directly in the first round.
--------------------------------------------------------
Dinamo București won 7–0 on aggregate.----5–5 on aggregate.
Rangers won 3–1 in a play-off.----Rapid Vienna won 5–0 on aggregate.----Panathinaikos won 5–4 on aggregate.----Köln won 2–0 on aggregate.----2–2 on aggregate.
0–0 in play-off; Anderlecht won coin toss.----Liverpool won 11–1 on aggregate.----Vasas ETO Győr won 6–2 on aggregate.----Lokomotiv Sofia won 8–5 on aggregate.----DWS won 4–1 on aggregate.----Lyn won 4–2 on aggregate.----Real Madrid won 9–2 on aggregate.----4–4 on aggregate.
0–0 in play-off; Dukla Prague won coin toss.----La Chaux-de-Fonds won 4–3 on aggregate.----Benfica won 10–2 on aggregate.
|}
----------------------------
Köln won 3–2 on aggregate.----Liverpool won 4–0 on aggregate.----Internazionale won 7–0 on aggregate.----Rangers won 3–0 on aggregate.----DWS won 8–1 on aggregate.----Vasas ETO Győr won 8–7 on aggregate.----Benfica won 6–1 on aggregate.----Real Madrid won 6–2 on aggregate.
|}
1 Liverpool advanced to the semi-finals by winning a coin toss after their play-off match ended 2–2.
------------
2–2 on aggregate; Liverpool won coin toss.----Internazionale won 3–2 on aggregate.----Vasas ETO Győr won 2–1 on aggregate.----Benfica won 6–3 on aggregate.
|}
----
Internazionale won 4–3 on aggregate.----Benfica won 5–0 on aggregate.
See main article: 1965 European Cup Final.
The top scorers from the 1964–65 European Cup (including preliminary round) are as follows:
