Eugene Koonin Explained

Eugene Koonin
Birth Name:Eugene V. Koonin
Birth Date:26 October 1956
Birth Place:Moscow
Citizenship:United States
Fields:Computational biology
Workplaces:National Center for Biotechnology Information
Alma Mater:Moscow State University (1978)
Thesis Title:Multienzyme organization of encephalomyocarditis virus replication complexes
Thesis Year:1983
Doctoral Advisor:Vadim I. Agol

Eugene Viktorovich Koonin (Russian: Евге́ний Ви́кторович Ку́нин; born October 26, 1956) is a Russian-American biologist and Senior Investigator at the National Center for Biotechnology Information (NCBI). He is a recognised expert in the field of evolutionary and computational biology.[1] [2] [3]

Education

Koonin gained a Master of Science in 1978 and a PhD in 1983 in molecular biology, both from the Department of Biology at Moscow State University. His PhD thesis, titled "Multienzyme organization of encephalomyocarditis virus replication complexes", was supervised by Vadim I. Agol.[4]

Research

From 1985 until 1991, Koonin worked as a research scientist in computational biology in the Institutes of Poliomyelitis and Microbiology at the USSR Academy of Medical Sciences, studying virus biochemistry and bacterial genetics. In 1991, Koonin moved to the NCBI, where he has held a Senior Investigator position since 1996.

Koonin's principal research goals include the comparative analysis of sequenced genomes and automatic methods for genome-scale annotation of gene functions.[5] He also researches in the application of comparative genomics for phylogenetic analysis, reconstruction of ancestral life forms and building large-scale evolutionary scenarios, as well as mathematical modeling of genome evolution.[6] [7] [8] Koonin's research also investigates computational study of the major transitions in the evolution of life, such as the origin of eukaryotes,[9] the evolution of eukaryotic signaling and developmental pathways from the comparative-genomic perspective.[10]

Koonin is an advocate of the extended evolutionary synthesis.[11]

In 2011 Koonin outlined his views on evolution in the book "The Logic of Chance: The Nature and Origin of Biological Evolution".

Career

Koonin has worked as adjunct professor at the Georgia Institute of Technology, Boston University and the University of Haifa.[12]

As of 2014, Koonin serves on the advisory editorial board of Trends in Genetics,[13] and is co-Editor-in-Chief of the open access journal Biology Direct.[14] He served on the editorial board of Bioinformatics from 1999 until 2001. Koonin is also an advisory board member in bioinformatics at Faculty of 1000.[15]

In 2016 he was elected to the National Academy of Sciences.[16] [17]

In 2016, Semantic Scholar AI program included Koonin on its list of top ten most influential biomedical researchers.[18]

Political positions

In February 2022, he signed an open letter by Russian scientists condemning the 2022 Russian invasion of Ukraine,[19] and renounced his membership in the Russian Academy of Sciences out of protest.[20]

Selected bibliography

Notes and References

  1. https://www.ncbi.nlm.nih.gov/CBBresearch/Koonin/ Koonin's page at the National Center for Biotechnology Information
  2. Book: Eugene V. Koonin. The Logic of Chance: The Nature and Origin of Biological Evolution. 5 April 2013. 23 June 2011. FT Press. 978-0-13-262317-9.
  3. 14986627. 2004. Koonin. E. V.. Eugene V. Koonin. Current Biology. 14. 3. R96–97. 10.1016/j.cub.2004.01.010. free.
  4. Web site: CV E. Koonin. Haifa Institute of Evolution. 28 July 2020. 29 July 2019. https://web.archive.org/web/20190729181259/http://evolution.haifa.ac.il/index.php/27-people/cv/160-cv-e-koonin-sp-24914. dead.
  5. E. S.. Lander. Eric Lander. Linton . M. . Birren . B. . Nusbaum . C. . Zody . C.. Baldwin . J. . Devon . K. . Dewar . K. . Doyle . M. . Fitzhugh . W. . Funke . R. . Gage . D. . Harris . K. . Heaford . A. . Howland . J. . Kann . L. . Lehoczky . J. . Levine . R. . McEwan . P. . McKernan . K. . Meldrim . J. . Mesirov . J. P. . Miranda . C. . Morris . W. . Naylor . J. . Raymond . C. . Rosetti . M. . Santos . R. . Sheridan . A. . Sougnez . C. . 29. Initial sequencing and analysis of the human genome . Nature . 409 . 6822 . 860–921 . Feb 2001 . 0028-0836 . 11237011 . 10.1038/35057062. 2001Natur.409..860L. free .
  6. Koonin . E. V. . Eugene Koonin. Bourne . Philip E. . Are There Laws of Genome Evolution? . 10.1371/journal.pcbi.1002173 . . 7 . 8 . e1002173 . 2011 . 21901087. 3161903. 1108.3589 . 2011PLSCB...7E2173K . free .
  7. Koonin . E. V. . Eugene Koonin. 10.1186/1745-6150-2-21 . The Biological Big Bang model for the major transitions in evolution . Biology Direct . 2 . 21 . 2007 . 17708768. 1973067 . free .
  8. Koonin . E. V. . Eugene Koonin. Senkevich . T. G. . Dolja . V. V. . The ancient Virus World and evolution of cells . Biology Direct . 1 . 29 . 2006 . 10.1186/1745-6150-1-29 . 16984643. 1594570 . free .
  9. Martin . William . Koonin . Eugene V. . Introns and the origin of nucleus–cytosol compartmentalization . Nature . 440 . 7080 . 2006 . 0028-0836 . 10.1038/nature04531 . 41–45.
  10. 11081625. 2000. Uhlmann. F . Frank Uhlmann. Cleavage of cohesin by the CD clan protease separin triggers anaphase in yeast. Cell. 103. 3. 375–386. Wernic. D. Poupart. M. A.. Koonin. E. V. . Eugene Koonin. Nasmyth. K . Kim Nasmyth. 10.1016/s0092-8674(00)00130-6. 2667617. free.
  11. Book: https://link.springer.com/chapter/10.1007/978-3-031-22028-9_11 . 10.1007/978-3-031-22028-9_11 . The Structure of Evolutionary Theory: Beyond Neo-Darwinism, Neo-Lamarckism and Biased Historical Narratives About the Modern Synthesis . Evolutionary Biology: Contemporary and Historical Reflections Upon Core Theory . Evolutionary Biology – New Perspectives on Its Development . 2023 . Svensson . Erik I. . 6 . 173–217 . 978-3-031-22027-2 .
  12. Web site: Faculty and Researchers. Haifa Institute of Evolution. 28 July 2020. 1 August 2019. https://web.archive.org/web/20190801005529/http://evolution.haifa.ac.il/index.php/people/faculty-a-researchers. dead.
  13. Web site: Masthead: Trends in Genetics. cell.com. 3 September 2014.
  14. Web site: Biology Direct – Editorial Board. biologydirect.com. 3 September 2014.
  15. Web site: Eugene Koonin: Advisory Board Member in Bioinformatics – F1000Prime. f1000.com. 3 September 2014.
  16. .
  17. Gabrielsen. Paul. 2017-01-31. Profile of Eugene V. Koonin. Proceedings of the National Academy of Sciences of the United States of America. 114. 5. 793–796. 10.1073/pnas.1621406114. 0027-8424. 28115717. 5293061. 2017PNAS..114..793G . free.
  18. Web site: Chawla. Dalmeet Singh. 17 October 2017 . Who's the most influential biomedical scientist? Computer program guided by artificial intelligence says it knows. 2022-02-16. Science AAAS. en.
  19. Web site: Открытое письмо российских учёных и научных журналистов против войны с Украиной . 24 February 2022 . 2 April 2022 . ru . An open letter from Russian scientists and scientific journalist against the war in Ukraine.
  20. Web site: Global Science Community Condemns Russian Invasion of Ukraine . . https://web.archive.org/web/20230312124910/https://www.scientificamerican.com/article/global-science-community-condemns-russian-invasion-of-ukraine/ . 2023-03-12 . live .

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