Eudesmic acid explained

Eudesmic acid is an O-methylated trihydroxybenzoic acid.

Natural Occurrence

It can be found in Eucalyptus spp.^[1]

Synthesis

Eudesmic acid is most directly synthesized by reaction of gallic acid with dimethyl sulfate.^[2]

Derivatives

1. Esterified with Deanol.^[3]
2. Trimebutine
3. Amoproxan
4. Bernzamide
5. 3,4,5-trimethoxy-N-(pyridin-4-yl)benzamide [31638-97-8].^[4]
6. Butobendine
7. Capobenic acid
8. Dilazep
9. Ecipramidil
10. Fepromide
11. Hexobendine
12. Mepramidil (Diphenamilate)
13. TMB-8 [57818-92-5]
14. Tricetamide (Trimeglamide)
15. Trimethobenzamide
16. Trimetozine
17. Tritiozine (ala trimetozine but thioamide).
18. Trocimine [14368-24-2]
19. Troxipide (Lefron)
20. Troxonium
21. Troxypyrrolium (Troxypyrrole, Trox)
22. Trimetamide.
23. Vinmegallate (RGH-4417)
24. Leonuramine and Leonurine.
25. Methoserpidine, Reserpine and Deserpidine.

Notes and References

1. HPLC analysis of flavonoids and phenolic acids and aldehydes in Eucalyptus spp. E. Conde, E. Cadahía and M. C. Garcia-Vallejo, Chromatographia, Volume 41, Numbers 11-12, 657-660,
2. Book: Ikan, Raphael. Natural Products: A Laboratory Guide 2nd Ed.. 1991. Academic Press, Inc.. San Diego. 0123705517. 232–235.
3. Ex25 in GB. 879259. 1961-10-11. Acid addition salts of 2-dimethylaminoethanol and central nervous system stimulant compositions containing them. Riker Laboratories Inc..
4. ES. 456989. 1978-07-16. Procedimiento de obtencion de un derivado de 4-aminopiridina y sus sales [Procedure for obtaining a 4-aminopyridine derivative and its salts]. Laboratorio Farmaceutico Quimico-Lafarquim SA. Sanjosé. Miguel Izquierdo. Ulpiano Martín-Escudero. Pérez.