| Type: | combo |
| Component1: | Ethambutol |
| Class1: | Anti-tuberculosis medication |
| Component2: | Isoniazid |
| Class2: | Anti-tuberculosis medication |
| Component3: | Pyrazinamide |
| Class3: | Anti-tuberculosis medication |
| Component4: | Rifampicin |
| Class4: | Anti-tuberculosis medication |
| Tradename: | Voractiv, Rimstar, others |
| Routes Of Administration: | By mouth |
| Cas Number: | 357397-87-6 |
| Atc Prefix: | J04A |
| Atc Suffix: | M06 |
| Chemspiderid: | none |
Ethambutol/isoniazid/pyrazinamide/rifampicin, also known as ethambutol/isoniazid/pyrazinamide/rifampin, is a medication used for tuberculosis. It is a fixed dose combination of ethambutol, isoniazid, pyrazinamide, and rifampicin. It is used either alone or with other antituberculosis medication. It is taken by mouth.[1]
Side effects are those of the underlying medications.[1] Pyridoxine may be used to decrease the risk of numbness.[2] It is not recommended in people with liver problems or severe kidney problems.[3] Use may not be suitable in children.[1] It is unclear if use during pregnancy is safe.[3]
It is on the World Health Organization's List of Essential Medicines.[4] It is sold under the brand names Voractiv and Rimstar in the UK.[3]