Estradiol valerate/methenmadinone caproate explained

Estradiol valerate/methenmadinone caproate (EV/MMC), known by the tentative brand name Lutofollin, is a combination medication of estradiol valerate (EV), an estrogen, and methenmadinone caproate (MMC; superlutin caproate), a progestin, which was developed for potential use as a once-a-month combined injectable contraceptive but was never marketed.^{[1] [2]} It contained 10 mg EV and 60 mg MMC in 1 mL oil solution and was intended for administration by intramuscular injection once every 4 weeks.

See also

• List of combined sex-hormonal preparations § Estrogens and progestogens

Notes and References

1. Stĕrba R . Tschechoslowakisches Injektionskontrazeptivum, einmal im Monat zu verabreichen . A Czechoslovak injection-contraceptive agent administered once a month . Zentralblatt für Gynakologie . de . January 1976 . 98 . 3 . 158–160 . 0044-4197 . 970015 .
2. Toppozada MK . Existing once-a-month combined injectable contraceptives . Contraception . 49 . 4 . 293–301 . April 1994 . 8013216 . 10.1016/0010-7824(94)90029-9 .