Estradiol hemisuccinate explained

Estradiol hemisuccinate (brand name Eutocol), or simply estradiol succinate, also known as estradiol 17β-hemisuccinate, is an estrogen medication and an estrogen ester – specifically, the hemisuccinate ester of estradiol.[1] It is used as a component of hormone replacement therapy for menopause. Like other estrogens, estradiol hemisuccinate has been found to have beneficial effects on the skin, with improvement of skin thickness observed.[2] [3]

Estradiol hemisuccinate is also a component of estradiol hemisuccinate/progesterone (brand name Hosterona), an injectable preparation used to induce withdrawal bleeding in women with amenorrhea.[4] [5] [6]

See also

Notes and References

  1. Book: Elks J . The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. 14 November 2014. Springer. 978-1-4757-2085-3. 897.
  2. Book: Thompson Z, Maibach HI . Biological Effects of Estrogen on Skin . Farage MA, Miller KW. Textbook of Aging Skin . 2010. 361–367 (362) . 10.1007/978-3-540-89656-2_35. 978-3-540-89655-5 . https://books.google.com/books?id=9-ALWZhXomAC&pg=PA362 .
  3. Maheux R, Naud F, Rioux M, Grenier R, Lemay A, Guy J, Langevin M . A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness . American Journal of Obstetrics and Gynecology . 170 . 2 . 642–649 . February 1994 . 8116726 . 10.1016/s0002-9378(94)70242-x .
  4. Web site: ¿Qué es Hosterona y para qué sirve? . What is Hosterona and what is it for? . es . matchmyrx.com . PRX Control Solutions . https://web.archive.org/web/20190413064051/https://matchmyrx.com/es/directorio/marca/hosterona . 13 April 2019 .
  5. Web site: Hosterona - Para qué sirve . Hosterona - What it is for . es . Los Medicamentos . 23 November 2012.
  6. Web site: HOSTERONA (Hormonoterapia) . Laboratorio GADOR .