Estradiol benzoate/progesterone/testosterone propionate explained

Estradiol benzoate/progesterone/testosterone propionate (EB/P4/TP), sold under the brand names Lukestra, Steratrin, Trihormonal, and Trinestryl, is an injectable combination medication of estradiol benzoate (EB), an estrogen, progesterone (P4), a progestogen, and testosterone propionate (TP), an androgen/anabolic steroid.[1] [2] [3] [4] [5] It contained 1 to 3 mg EB, 20 to 25 mg P4, and 25 mg TP, was provided in the form of ampoules, and was administered by intramuscular injection.[6] The medication was introduced by 1949 and was marketed in the United States, the United Kingdom, and Germany among other places.[7] [8] It is no longer available.[9] [10]

See also

Notes and References

  1. Book: Silló G . Komplexhormon bei Menopause und Hypertonie . Complex hormone for menopause and hypertension . Nowakowski H . Hormone und Psyche die Endokrinologie des Alternden Menschen: Fünftes Symposion der Deutschen Gesellschaft für Endokrinologie Freiburg (Breisgau), den 7. bis 9. März 1957 . Hormones and Psyche the Endocrinology of Aging People: Fifth Symposium of the German Society for Endocrinology Freiburg (Breisgau), March 7th to 9th, 1957 . https://books.google.com/books?id=4NKEBwAAQBAJ&pg=PA55. 9 March 2013. Springer-Verlag. 978-3-642-87014-9. 55–.
  2. Book: Hager HH, Kern W, List PH, Roth HJ . Hormone . Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Ärzte und Medizinalbeamte: Wirkstoffgruppen II Chemikalien und Drogen (A-AL). https://books.google.com/books?id=a2a0BgAAQBAJ&pg=PA187. 29 July 2013. Springer-Verlag. 978-3-662-25655-8. 187–.
  3. Book: Walther K, Auterhoff H, Neuwald F, Schmid W . Hormone . Hagers Handbuch der Pharmazeutischen Praxis: Für Apotheker, Arzneimittelhersteller, Drogisten, Ärzte und Medizinalbeamte. https://books.google.com/books?id=C_SgBgAAQBAJ&pg=PA1163. 9 March 2013. Springer-Verlag. 978-3-642-49759-9. 1163–.
  4. Book: Ufer J . Hormontherapie in der Frauenheilkunde: Grundlagen und Praxis. 1960. de Gruyter. 155. 9783111138770 .
  5. Book: Bishop PM . Chemistry of the Sex Hormones. 1962. Thomas. 85. Lukestra Injection Steroid Triad (oestradiol benz., test. prop. and progesterone) Merck, Sharp & Dohme.
  6. Greenblatt RB, Barfield WE . Hormonal control of functional uterine bleeding . American Journal of Obstetrics and Gynecology . 63 . 1 . 153–157 . January 1952 . 14894511 . 10.1016/s0002-9378(16)38992-x . The estrogen-progesterone-testosterone combinations used in our studies were supplied by the following pharmaceutical companies: Wyeth, Inc.: Tristerone (6 mg. estrone, 50 mg. progesterone, 25 mg. testosterone). Schering Corporation: Steratrin (1 mg. estradiol benzoate, 25 mg. progesterone, 25 mg. testoterone propionate).Sharp and Dohme, Inc.: Lukestra (1.66 mg. estradiol benzoate, 25 mg. progesterone, 25 mg. testosterone propionate). . 6863371 .
  7. Book: United States. Patent Office. Official Gazette of the United States Patent Office. 1950. U.S. Patent Office.. 31–.
  8. Book: Unlisted Drugs. 1952. Unlisted Drugs Committee of the Pharmaceutical Section, Science-Technology Group, Special Libraries Association. Lukestra C. each cc, contains: estradiol benzoate, 1.67 mg.; progesterone, 25 mg.; and testosterone propionate, 25 mg..
  9. Web site: ? . IBM Watson Health .
  10. Web site: Estradiol . Drugs.com .

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