Estradiol benzoate/testosterone propionate explained

Estradiol benzoate/testosterone propionate (EB/TP), sold under the brand name Bothermon, is an injectable combination medication of estradiol benzoate (EB), an estrogen, and testosterone propionate (TP), an androgen/anabolic steroid.^{[1] [2] [3] [4] [5]} It contains 0.24 mg/mL EB and 4.76 mg/mL TP in oil solution in each ampoule and is administered by intramuscular injection. The medication was marketed in Japan by 1953 and remains available in this country today.

See also

• List of combined sex-hormonal preparations

Notes and References

1. 伴一郎, & 杉山陽一. (1956). 男性ホルモンと黄体ホルモンとの混合製剤 Testoluton の使用成績. [Testoluton (Schering), A Combined Preparation of Testosterone Propionate and Progesterone Applied for Clinical Use] 産婦人科の進歩, 8(2), 100-103. https://www.jstage.jst.go.jp/article/sanpunosinpo1949/8/2/8_2_100/_pdf
2. 村上清. (1959). 産科婦人科的ホルモン療法の概況 (本邦). [Overview of obstetrics and gynecology hormone therapy (in Japan).] 産婦人科の進歩, 11(Special), 6-30. https://www.jstage.jst.go.jp/article/sanpunosinpo1949/11/Special/11_Special_6/_pdf
3. 山村博三. (1956). 機能性子宮出血の性ホルモン療法. [Sex hormone therapy for functional uterine bleeding.] 関西医科大学雑誌, 8(4), 293-299. https://www.jstage.jst.go.jp/article/jkmu1956/8/4/8_293/_pdf
4. 植田安雄, & 辻井翠. (1953). 月経困難症に対する Androgenestrogen 混合剤 Bothermon の応用 (治療成績). [Application of Androgenestrogen Bothermon for dysmenorrhea (treatment results).] ホルモンと臨床, 1(4), 333-337. https://ci.nii.ac.jp/naid/40018513715/
5. Web site: Archived copy . 2019-06-09 . 2019-04-07 . https://web.archive.org/web/20190407210211/https://www.drugs.com/international/bothermon.html . dead .