Estradiol disulfate explained

Estradiol disulfate (also known as E2DS or estradiol 3,17β-disulfate) is an endogenous estrogen conjugate and metabolite of estradiol. It is related to estradiol 3-sulfate and estradiol 17β-sulfate. Estradiol disulfate has 0.0004% of the relative binding affinity of estradiol for the estrogen receptor alpha (ERα), one of the two estrogen receptors (ERs).^[1]

See also

• Catechol estrogen
• Estrogen conjugate
• Lipoidal estradiol
• List of estrogen esters § Estradiol esters

Notes and References

1. Durmaz V, Schmidt S, Sabri P, Piechotta C, Weber M . Hands-off linear interaction energy approach to binding mode and affinity estimation of estrogens . J Chem Inf Model . 53 . 10 . 2681–8 . October 2013 . 24063761 . 10.1021/ci400392p .