Estradiol 17β-sulfate explained

Estradiol 17β-sulfate is an estrogen conjugate which is produced from estradiol by sulfation of the C17β hydroxyl group by estrogen sulfotransferases.[1] [2] [3] [4]

See also

Notes and References

  1. Yoshizawa I, Takanashi K, Watanabe K, Sato T, Honjo H, Tanaka K, Sakuragi N, Fujimoto S . The physiological role of estradiol 17-sulfate during pregnancy . J. Steroid Biochem. Mol. Biol. . 41 . 3–8 . 567–70 . March 1992 . 1314078 . 10.1016/0960-0760(92)90385-v. 42879796 .
  2. Honjo H . [Endogenous levels and dynamics of estrogen sulfates--physiological and pathological roles of estrone sulfate and estradiol 17-sulfate] . ja . Nihon Naibunpi Gakkai Zasshi . 68 . 11 . 1158–66 . November 1992 . 1468592 . 10.1507/endocrine1927.68.11_1158. free .
  3. Wang LQ, James MO . Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate . J. Steroid Biochem. Mol. Biol. . 96 . 5 . 367–74 . September 2005 . 16011896 . 10.1016/j.jsbmb.2005.05.002 . 24671971 .
  4. Brooks SC, Horn L . Hepatic sulfation of estrogen metabolites . Biochim. Biophys. Acta . 231 . 1 . 233–41 . February 1971 . 4323008 . 10.1016/0005-2760(71)90272-4 .

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