| Esterzili | |
| Official Name: | Comune di Esterzili |
| Native Name: | Istersili |
| Pushpin Map: | Italy Sardinia |
| Coordinates: | 39.7833°N 26°W |
| Region: | Sardinia |
| Mayor: | Giovanna Melis |
| Area Total Km2: | 100.5 |
| Population Total: | 743 |
| Population As Of: | 30 November 2010[1] |
| Population Demonym: | Esterzilesi |
| Elevation M: | 731 |
| Postal Code: | 08030 |
| Area Code: | 0782 |
Esterzili, Istersili or Stersili in sardinian language, is a comune (municipality) in the Province of South Sardinia in the Italian region Sardinia, located about 100km (100miles) north of Cagliari.
Esterzili borders the following municipalities: Escalaplano, Nurri, Orroli, Sadali, Seui, Ulassai.