Esprit-Saint should not be confused with Saint-Esprit, Quebec.
| Esprit-Saint | |
| Settlement Type: | Municipality |
| Pushpin Map: | Canada Eastern Quebec |
| Pushpin Map Caption: | Location in eastern Quebec |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Type2: | Region |
| Subdivision Name2: | Bas-Saint-Laurent |
| Subdivision Type3: | RCM |
| Subdivision Name3: | Rimouski-Neigette |
| Established Title1: | Constituted |
| Established Date1: | May 13, 1972 |
| Named For: | The Holy Spirit the third person of the Trinity |
| Leader Title: | Mayor |
| Leader Name: | Marlène Dubé |
| Leader Title1: | Federal riding |
| Leader Name1: | Rimouski-Neigette—Témiscouata—Les Basques |
| Leader Title2: | Prov. riding |
| Leader Name2: | Rimouski |
| Area Total Km2: | 169.40 |
| Area Land Km2: | 169.40 |
| Population Total: | 341 |
| Population As Of: | 2016 |
| Population Density Km2: | 2 |
| Population Blank1 Title: | Pop 2011-2016 |
| Population Blank1: | 10% |
| Population Blank2 Title: | Dwellings |
| Population Blank2: | 209 |
| Timezone: | EST |
| Utc Offset: | −5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | −4 |
| Postal Code Type: | Postal code(s) |
| Postal Code: | G0K 1A0 |
| Area Code: | 418 and 581 |
| Blank Name: | Highways |
Esprit-Saint is a municipality in Rimouski-Neigette Regional County Municipality in the Bas-Saint-Laurent region of Quebec, Canada. Its population as of the Canada 2016 Census was 341.