| Esnes-en-Argonne | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Esnes-en-Argonne 55.svg |
| Arrondissement: | Verdun |
| Canton: | Clermont-en-Argonne |
| Insee: | 55180 |
| Postal Code: | 55100 |
| Mayor: | Véronique Adler[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Argonne-Meuse |
| Coordinates: | 49.2086°N 5.2119°W |
| Elevation M: | 127 |
| Elevation Min M: | 205 |
| Elevation Max M: | 311 |
| Area Km2: | 14.76 |
Esnes-en-Argonne (in French pronounced as /ɛn ɑ̃.n‿aʁɡɔn/, literally Esnes in Argonne) is a commune in the Meuse department in Grand Est in north-eastern France.