| Esmoulières | |
| Commune Status: | Commune |
| Coordinates: | 47.8533°N 6.6161°W |
| Insee: | 70217 |
| Postal Code: | 70310 |
| Arrondissement: | Lure |
| Canton: | Mélisey |
| Elevation Min M: | 367 |
| Elevation Max M: | 674 |
| Area Km2: | 20.11 |
Esmoulières is a commune in the Haute-Saône department in the region of Bourgogne-Franche-Comté in eastern France. The dwarf chansonnier Auguste Tuaillon (1873–1907) was born in Esmoulières.