| Official Name: | Esmailiyeh-ye Do |
| Native Name: | اسماعيليه دو |
| Settlement Type: | village |
| Pushpin Map: | Iran |
| Mapsize: | 150px |
| Subdivision Type: | Country |
| Subdivision Type1: | Province |
| Subdivision Name1: | Khuzestan |
| Subdivision Type2: | County |
| Subdivision Name2: | Karun |
| Subdivision Type3: | Bakhsh |
| Subdivision Name3: | Soveyseh |
| Subdivision Type4: | Rural District |
| Subdivision Name4: | Muran |
| Population As Of: | 2006 |
| Population Total: | 615 |
| Population Density Km2: | auto |
| Timezone: | IRST |
| Utc Offset: | +3:30 |
| Timezone Dst: | IRDT |
| Utc Offset Dst: | +4:30 |
| Coordinates: | 31.0361°N 48.4114°W |
Esmailiyeh-ye Do (Persian: اسماعيليه دو, also Romanized as Esmā‘īlīyeh-ye Do; also known as Esmā ‘Eynī, Esmā‘īlīyeh, and Ismaun) is a village in Muran Rural District, in the Soveyseh District of Karun County, Khuzestan Province, Iran. At the 2006 census, its population was 615, in 130 families.