| Eseniu | |
| Name Other: | Eszenyő-patak |
| Pushpin Map: | Romania |
| Subdivision Type1: | Country |
| Subdivision Name1: | Romania |
| Subdivision Type2: | Counties |
| Subdivision Name2: | Harghita County |
| Subdivision Type3: | Villages |
| Subdivision Name3: | Sineu |
| Length: | 17km (11miles) |
| Source1: | Gurghiu Mountains |
| Mouth: | Mureș |
| Mouth Location: | Remetea |
| Mouth Coordinates: | 46.811°N 25.461°W |
| Basin Size: | 28km2 |
The Eseniu (Hungarian: Eszenyő-patak) is a small river in the Gurghiu Mountains, Harghita County, central Romania. It is a left tributary of the river Mureș. It flows through the village Sineu (municipality Remetea), and joins the Mureș in the village Remetea. Its length is 17km (11miles) and its basin size is 28km2.