| Official Name: | Escuintla Department |
| Native Name: | Departmento de Escuintla |
| Native Name Lang: | es |
| Settlement Type: | Department of Guatemala |
| Seal Size: | 75px |
| Mapsize: | 300 |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Guatemala |
| Subdivision Type: | Country |
| Subdivision Name: | Guatemala |
| Seat Type: | Capital |
| Seat: | Escuintla |
| Parts Type: | Municipalities |
| Parts: | 13 |
| Government Type: | Departmental |
| Leader Title: | Governor |
| Area Total Km2: | 4384 |
| Population As Of: | 2018 |
| Population Footnotes: | [1] |
| Population Total: | 733181 |
| Population Density Km2: | auto |
| Population Urban: | 448531 |
| Population Blank1 Title: | Ethnicities |
| Population Blank1: | Ladino, Poqomam |
| Population Blank2 Title: | Religions |
| Population Blank2: | Roman Catholicism, Evangelicalism |
| Utc Offset: | -6 |
| Coordinates: | 14.2978°N -90.7869°W |
| Iso Code: | GT-ES |
Escuintla (pronounced as /es/) is one of the 22 departments of Guatemala. The capital of the department is the city of Escuintla. Escuintla covers an area of 4,384 km2 and is situated in the coastal lowland region, directly south of Guatemala City, and bordered by the Pacific Ocean. Escuintla produces about 43 percent of gross domestic product of Guatemala.