| Escles | |
| Commune Status: | Commune |
| Arrondissement: | Neufchâteau |
| Canton: | Darney |
| Insee: | 88161 |
| Postal Code: | 88260 |
| Mayor: | Patrick Vagner[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CC Vosges côté Sud-Ouest |
| Coordinates: | 48.1297°N 6.1786°W |
| Elevation M: | 330 |
| Elevation Min M: | 285 |
| Elevation Max M: | 420 |
| Area Km2: | 22.54 |
Escles (pronounced as /fr/) is a commune in the Vosges department in Grand Est in northeastern France.
The river Madon flows through the commune.