| Esanatham | |
| Other Name: | Isanatham |
| Settlement Type: | village |
| Pushpin Map: | India Tamil Nadu#India |
| Pushpin Label Position: | right |
| Pushpin Map Caption: | Location in Tamil Nadu, India |
| Coordinates: | 10.7077°N 78.0027°W |
| Subdivision Type: | Country |
| Subdivision Name: |  India |
| Subdivision Type1: | State |
| Subdivision Name1: | Tamil Nadu |
| Subdivision Type2: | District |
| Subdivision Name2: | Karur |
| Unit Pref: | Metric |
| Population Density Km2: | auto |
| Demographics Type1: | Languages |
| Demographics1 Title1: | Official |
| Demographics1 Info1: | Tamil |
| Timezone1: | IST |
| Utc Offset1: | +5:30 |
| Postal Code Type: | PIN |
| Postal Code: | 639203 |
| Area Code Type: | Telephone code |
| Area Code: | 04320 |
| Registration Plate: | TN 47 |
| Blank1 Name Sec1: | Nearest city |
| Blank1 Info Sec1: | Karur |
| Blank3 Name Sec1: | Literacy |
| Blank3 Info Sec1: | 75% |
| Blank4 Name Sec1: | Lok Sabha constituency |
| Blank4 Info Sec1: | Karur |
| Blank5 Name Sec1: | Vidhan Sabha constituency |
| Blank5 Info Sec1: | Aravakurichi |
Esanatham is a village in Tamil Nadu, India. It is part of Karur District and surrounded by villages of the Dindigul district.
According to the latest 2020 Indian census, Esanatham has a population of 10056 consisting of 2023 families. The male population is 6089 and the female population is 3967 with 9.81% of the population under five years of age. The literacy rate is 75.12%, which is lower than the state average of 80.09%. Literacy stands at 86.31% for men and 64.55% for women. The sex ratio is 1040 which is comparable to the state ratio of 996.
15.44% of the population are members of a Scheduled Caste (SC).
2708 residents of Esanatham are engaged in work activities.