Envelysin Explained

Envelysin
Ec Number:3.4.24.12
Cas Number:50812-13-0

Envelysin (sea-urchin-hatching proteinase, hatching enzyme, chorionase, chorion-digesting proteinase, chymostrypsin, sea urchin embryo hatching enzyme) is an enzyme.[1] [2] [3] [4] This enzyme catalyses the following chemical reaction

Hydrolysis of proteins of the fertilization envelope and dimethylcasein

This enzyme is a glycoprotein from various members of the class Echinoidea.

Notes and References

  1. Book: Barrett D, Edwards BF . Hatching enzyme of the sea urchin Strongylocentrotus purpuratus . Part B: Proteolytic Enzymes . Methods in Enzymology . 45 . 354–73 . 1976 . 1012003 . 10.1016/s0076-6879(76)45032-2 . 978-0-12-181945-3 .
  2. Lepage T, Gache C . Purification and characterization of the sea urchin embryo hatching enzyme . The Journal of Biological Chemistry . 264 . 9 . 4787–93 . March 1989 . 10.1016/S0021-9258(18)83659-6 . 2925668 . free .
  3. Lepage T, Gache C . Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo . The EMBO Journal . 9 . 9 . 3003–12 . September 1990 . 10.1002/j.1460-2075.1990.tb07493.x . 2167841 . 552018 .
  4. Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N . The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family . Biochemistry . 30 . 25 . 6115–23 . June 1991 . 1711895 . 10.1021/bi00239a005 .

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