| Official Name: | Entresierras |
| Settlement Type: | Comarca |
| Subdivision Type: | Country |
| Subdivision Name: | Spain |
| Subdivision Type1: | Autonomous community |
| Subdivision Type2: | Province |
| Subdivision Name1: | Castile and León |
| Subdivision Name2: | Salamanca |
| Subdivision Type3: | Comarca |
| Subdivision Name3: | Comarca de Guijuelo |
| Area Total Km2: | 234.18 |
| Population Total: | 1,618 |
| Population As Of: | 2010 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Coordinates: | 40.5681°N -5.7875°W |
Entresierras is a subcomarca of Guijuelo in the province of Salamanca, Castile and León, Spain. It contains the municipalities of Casafranca, Endrinal, Frades de la Sierra, Herguijuela, La Sierpe, Los Santos, Membribe de la Sierra and Monleón.[1]