| Enrique Oyarzún | |
| Birth Date: | 1860 6, df=y |
| Birth Place: | Vallenar, Chile |
| Death Place: | Santiago, Chile |
| Nationality: | Chilean |
| Office1: | President of the Senate of the Republic of Chile |
| Term Start1: | 1 March 1925 |
| Term End1: | 15 March 1930 |
| Predecessor1: | Eliodoro Yáñez |
| Successor1: | Pedro Opaso |
| Party: | Radical Party |
| Occupation: | Politician |
| Profession: | Lawyer and Teacher of Spanish language |
Enrique Oyarzún Mondaca (born 20 June 1860–19 August 1849) was a Chilean politician, lawyer and teacher of Spanish language who served as President of the Senate of Chile.