| Honorific-Prefix: | The Honourable |
| Enrique B. Magalona | |
| Birth Name: | Enrique Magalona y Barrera |
| Birth Date: | 1891 11, mf=yes[1] |
| Birth Place: | Saravia, Negros Occidental, Captaincy General of the Philippines |
| Death Place: | Philippines |
| Office1: | Senator of the Philippines |
| Term Start1: | May 28, 1946 |
| Term End1: | December 30, 1955 |
| Office2: | Member, House of Representatives of the Philippines from Negros Occidental's 1st district |
| Term Start2: | June 2, 1931 |
| Term End2: | May 25, 1946 |
| Predecessor2: | Jose C. Locsin |
| Successor2: | Vicente F. Gustilo Sr. |
| Alma Mater: | San Juan de Letran |
| Spouse: | Consuelo Gayoso[2] |
| Children: | 3 (including Pancho) |
| Parents: | Vicente Magalona y Ledesma (father) Augusta Barrera y Majarocan (mother) |
| Party: | Liberal (1946–1955) Nacionalista (1922-1946) |
| Profession: | Senator,[3] Lawyer |
Enrique "Equi" Barrera Magalona Sr. (November 5, 1891 – 1960) was a Filipino lawyer and politician who served as a Senator of the Philippines. Prior to being elected to the Senate, he served as the Municipal President of Saravia, Negros Occidental, which is now named in his honor, and as a Representative from Negros Occidental in the Philippine Assembly. He was the grandfather of the late Filipino rapper Francis Magalona.
Enrique B. Magalona was born in Saravia, Negros Occidental (now Enrique B. Magalona, Negros Occidental) on November 5, 1891 to Vicente Magalona y Ledesma and Augusta Barrera y Majarocan.
He was married to Consuelo Lozada Gayoso with 3 children including Enrique G. Magalona, Jr.
He studied in Molo Institute, Iloilo where he obtained both his primary and secondary education. He graduated at San Juan de Letran with the degree of Bachelor of Arts in 1907 and La Jurisprudencia where he received his Bachelor of Laws degree in 1911.
He was elected Municipal President of Saravia in 1922 and re-elected to the same post in 1925. In 1926, he was elected President of the Municipal Presidents Convention at Bacolod, Negros Occidental. Senator Magalona was elected representative to the ninth and tenth Philippine Legislature from 1931 to 1934, and then, later elected assemblyman from the first district of Negros Occidental in 1935 and re-elected in 1938. He was elected Senator for two terms from 1946 to 1949 and from 1949 to 1955. Senator Magalona was chairman of the Committees on Accounts and Civil Service; Rules; Public Health; Labor and Immigration and National Exterprises. As lawmaker he authored, among others Republic Act. 342 (Moratorium Act); R.A. 611 (cumulative computation of vacation and sick leaves) and R.A. No. 709 (instruction of Spanish in colleges and universities).
Enrique Magalona, Sr. died in Manila, Philippines in 1960.