| E. Walter Sikes | |
| Birth Date: | 19 May 1868 |
| Birth Place: | Union County, North Carolina, U.S. |
| Death Place: | Clemson, South Carolina, U.S. |
| Player Years1: | 1889–1892 |
| Player Team1: | Wake Forest |
| Player Positions: | Guard |
| Coach Years1: | 1891–1893 |
| Coach Team1: | Wake Forest |
| Overall Record: | 6–2–1 |
Enoch Walter Sikes (May 19, 1868 – January 8, 1941) was an American college football player and coach, professor, state senator, and university president. He served as the head football coach at Wake Forest University from 1891 to 1893, compiling a record of 6–2–1. Sikes taught history and political economics at Wake Forest from 1897 to 1916. He served one term in the North Carolina Senate, representing Wake County in 1911. Sikes was the president of Coker College from 1916 to 1925 and the president of Clemson University from 1925 until his retirement in 1940 He died of a heart attack on January 8, 1941, in Clemson, South Carolina.[1] [2]