| Official Name: | Encina de San Silvestre |
| Settlement Type: | Municipality |
| Flag Size: | 150 |
| Pushpin Map: | Spain |
| Pushpin Map Caption: | Location in Spain |
| Coordinates: | 41.0139°N -6.0931°W |
| Subdivision Type: | Country |
| Subdivision Name: | Spain |
| Subdivision Type1: | Autonomous community |
| Subdivision Name1: | Castile and León |
| Subdivision Type2: | Province |
| Subdivision Name2: | Salamanca |
| Subdivision Type3: | Comarca |
| Subdivision Name3: | Tierra de Ledesma |
| Leader Party: | People's Party |
| Leader Title: | Mayor |
| Leader Name: | José Luis Vicente |
| Area Footnotes: | [1] |
| Area Total Km2: | 23.76 |
| Elevation M: | 800 |
| Population Footnotes: | [2] |
| Population Total: | 111 |
| Population As Of: | 2016 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Postal Code Type: | Postal code |
| Postal Code: | 37114 |
Encina de San Silvestre is a village and municipality in the province of Salamanca, western Spain, part of the autonomous community of Castile and León. It is located from the provincial capital city of Salamanca and has a population of 111 people.
The municipality covers an area of 23.76km2.
It lies above sea level.
The postal code is 37114.
Spanish poet and musician Juan del Enzina was born in the village.