| Emmanuel Mission School | |
| Motto: | The fear of the Lord is the beginning of wisdom |
| Location: | BSF Camp Road Jaisalmer 345001 India |
| Principal: | Rev. V. A. Samuel |
| Sister School: | Emmanuel Mission Senior Secondary School, Kota |
| Colours: | Olive green and White |
| Founder: | Father M.A. Thomas |
| Gender: | Girls and Boys |
| Lower Age: | 3 |
| Upper Age: | 18 |
| Houses: | 5 |
| Campus: | 12 acres |
| Free Label: | Former pupils |
| Free Text: | Emmanuelites |
| Students: | 1000 |
Emmanuel Mission Senior Secondary School is a co-educational English-medium high school located in Jaisalmer, a town in the state of Rajasthan, India. The school is affiliated to the Central Board of Secondary Education (CBSE).
The school was established by Father M. A. Thomas and his wife Mrs Sosamma Samuel in the border town of Jaisalmer in the year 1984. The school was started in a small rented space in the city and was shifted to its present location in the year 1990. The school was initially affiliated to Board of Secondary Education, Rajasthan but in the year 2008 the school got affiliated to Central Board of Secondary Education, Delhi.The school belongs to Emmanuel Society.
Emmanuel (Immanuel) is a Hebrew word meaning "God is with us".