Eleftheria Maratos-Flier Explained

Eleftheria Maratos-Flier is an American endocrinologist,[1] and emerita Professor of Medicine at Harvard Medical School,[2] best known for her expertise in the pathophysiology and prevention of obesity-related metabolic disorders,[3] [4] and for her discoveries on the neuroendocrine control of feeding behaviour.[5] [6] She is a contributing author to known textbooks and reviews in internal medicine,[7] endocrinology,[8] and physiology.[9] Her marriage with professor Jeffrey Flier, was noted by Forbes[10] as a lasting and productive bond between eminent medical scholars.[11] They have two adult daughters who are also physicians. She is also known as Terry Maratos-Flier.[12]

Education

In 1972, she graduated with a BA in Chemistry from New York University, New York, NY.[13] In 1976, she graduated as an MD from the Mount Sinai School of Medicine, New York, NY, followed by internship and residency training in internal medicine at George Washington University Hospital, Washington, DC.[14] In Massachusetts (1978-1981), she pursued further residency training in internal medicine at Beth Israel Hospital, postdoctoral research fellowship at Harvard School of Public Health, and Clinical Fellowship at the Joslin Diabetes Center and Brigham and Women’s Hospital.

Career

Since 1982 she has taught at Harvard Medical School, becoming a full Professor of Medicine from 2010 to 2018, when she became professor emerita.[15] She has been an associate member of the Broad Institute,[16] and a Principal Investigator of many NIH-funded research grants.[17] She has also been an attending endocrinologist at Beth Israel Deaconess Medical Center, where she still provides care for patients with metabolic disease.[18] From 2018, she has been Director, Translational Medicine, at Novartis Institutes of Biomedical Research, Cambridge, MA.,[19] recently moving to Alnylam to serve as a director of clinical research. She has authored more than 100 peer-reviewed papers, most of them studying aspects of obesity and type II diabetes in experimental mouse models, and also in clinical disease. She also authored the obesity chapters of the 20th edition of Harrison's Principles of Internal Medicine (jointly with Jeffrey Flier), and the 14th edition of Williams Textbook of Endocrinology. In 2016, she contributed an article to the Annual Review of Physiology on the physiology of Fibroblast Growth Factor 21.

Awards

Selected works

Maratos-Flier's research papers have been cited over 15,600 times.[22] Her most cited papers are:

References

  1. Web site: 2020-03-05 . Meet the 2020 Laureates: Eleftheria Maratos-Flier, MD . 2022-03-19 . Endocrine News . en-US.
  2. Web site: SSIB 2017 MARS Speakers . 2022-03-19 . www.ssib.org.
  3. Flier . Jeffrey S. . Maratos-Flier . Eleftheria . 2007 . What Fuels Fat . Scientific American . en . 297 . 3 . 72–81 . 2007SciAm.297c..72F . 10.1038/scientificamerican0907-72 . 17784627 . 2022-03-18.
  4. Web site: 2017-05-08 . Can't resist candy? You may have this mutation . 2022-03-18 . PBS NewsHour . en-us.
  5. Ahima . Rexford S. . Prabakaran . Daniel . Mantzoros . Christos . Qu . Daqing . Lowell . Bradford . Maratos-Flier . Eleftheria . Flier . Jeffrey S. . 1996-07-01 . Role of leptin in the neuroendocrine response to fasting . Nature . en . 382 . 6588 . 250–252 . 1996Natur.382..250A . 10.1038/382250a0 . 0028-0836 . 8717038 . 4331304.
  6. Qu . Daqing . Ludwig . David S. . Gammeltoft . Steen . Piper . Megan . Pelleymounter . Mary Ann . Cullen . Mary Jane . Mathes . Wendy Foulds . Przypek . Jeanne . Kanarek . Robin . Maratos-Flier . Eleftheria . 1996-03-01 . A role for melanin-concentrating hormone in the central regulation of feeding behaviour . Nature . en . 380 . 6571 . 243–247 . 1996Natur.380..243Q . 10.1038/380243a0 . 0028-0836 . 8637571 . 42701304.
  7. Book: Flier . Jeffrey S. . Harrison's principles of internal medicine . Maratos-Flier . Eleftheria . McGraw Hill . Chapter 394: Pathobiology of Obesity . 2018 . 978-1-259-64403-0 . 20th . New York . 1029074059.
  8. Book: Maratos-Flier, Elephteria . Obesity chapter in Williams textbook of endocrinology . 2020 . Saunders . Shlomo Melmed, Richard J. Auchus, Allison B. Goldfine, Ronald Koenig, Clifford J. Rosen, Robert Hardin Preceded by: Williams . 978-0323555968 . 14 . Philadelphia, PA . 1567–1580, Obesity chapter . 1131863622.
  9. Fisher . Ffolliott Martin . Maratos-Flier . Eleftheria . 2016 . Understanding the Physiology of FGF21 . Annual Review of Physiology . 78 . 223–241 . 10.1146/annurev-physiol-021115-105339 . 1545-1585 . 26654352. free .
  10. Web site: Shaywitz . David . Power couples: common in medicine, rare in business? . 2022-03-02 . Forbes . en.
  11. Flier . Jeffrey S. . 2012-09-01 . Hormone resistance in diabetes and obesity: insulin, leptin, and FGF21 . The Yale Journal of Biology and Medicine . 85 . 3 . 405–414 . 1551-4056 . 3447204 . 23012588.
  12. Web site: ORCID . 2022-03-02 . orcid.org.
  13. 1971-10-01 . American Chemical Society Award Winners, Washington, D.C. . Analytical Chemistry . en . 43 . 12 . 63A–73A . 10.1021/ac60306a706 . 0003-2700.
  14. Web site: Eleftheria Maratos-Flier, MD .
  15. Web site: New Appointments to Full Professor (12/22/10) . 2022-03-19 . hms.harvard.edu . en.
  16. Web site: 2008-04-23 . Team . 2022-03-19 . Broad Institute . en.
  17. Web site: Eleftheria Maratos-Flier . grantome.com.
  18. Web site: Meet Our Endocrinology, Diabetes and Metabolism Experts . 2022-03-19 . www.bidmc.org . en-us.
  19. Rader . Daniel J. . Maratos-Flier . Eleftheria . Nguyen . Amanda . Hom . Doug . Ferriere . Michael . Li . Yifang . Kompa . Jill . Martic . Miljen . Hinder . Markus . Basson . Craig T. . Yowe . David . 2022-01-01 . LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in Obese Adults With Modest Hypertriglyceridemia . The Journal of Clinical Endocrinology and Metabolism . 107 . 1 . e57–e70 . 10.1210/clinem/dgab624 . 1945-7197 . 8914500 . 34431493 .
  20. Web site: Alumni Award Recipients . 2022-03-19 . alumni.icahn.mssm.edu . en.
  21. Web site: 2020-10-05 . An Appetite for Research: Q&A with Eleftheria Maratos-Flier, MD . 2022-03-02 . Endocrine News . en-US.
  22. Web site: Scopus preview - Maratos-Flier, Eleftheria - Author details - Scopus . 2022-03-19 . www.scopus.com.
  23. Badman . Michael K. . Pissios . Pavlos . Kennedy . Adam R. . Koukos . George . Flier . Jeffrey S. . Maratos-Flier . Eleftheria . 2007-06-01 . Hepatic Fibroblast Growth Factor 21 Is Regulated by PPARα and Is a Key Mediator of Hepatic Lipid Metabolism in Ketotic States . Cell Metabolism . en . 5 . 6 . 426–437 . 10.1016/j.cmet.2007.05.002 . 17550778. free .
  24. Fisher . ffolliott M. . Kleiner . Sandra . Douris . Nicholas . Fox . Elliott C. . Mepani . Rina J. . Verdeguer . Francisco . Wu . Jun . Kharitonenkov . Alexei . Flier . Jeffrey S. . Maratos-Flier . Eleftheria . Spiegelman . Bruce M. . 2012-02-01 . FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis . Genes & Development . en . 26 . 3 . 271–281 . 10.1101/gad.177857.111 . 0890-9369 . 3278894 . 22302939.

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